In this study, 920 subjects with a diagnosis of IBS but who don't have Celiac disease based on blood testing, underwent an elimination diet and became symptomatic after they ate food that they were sensitive to.
- This was a good study because there was a control group to compare against. More importantly, they also "blinded" the process by hiding the food they were testing inside capsules so that the placebo or the nocebo (like when somebody feels bad after eating something they believe is bad for them, the opposite of placebo where someone feels better after taking something they believe is good for them) could be accounted for.
- Of those who developed symptoms after a blind food challenge, about 25% had symptoms when they ate wheat; the other 75% had multiple food sensitivities.
- A biopsy of the intestines of those who showed IBS symptoms was carried out.
- Among those sensitive to wheat, the biopsies show inflammatory changes in the tissue similar to Celiac disease--even though the blood tests show that these subjects supposedly did not have any Celiac disease.
- Among those who had multiple food sensitivites, the biopsy show changes that were similar to what you might see with someone who has allergies.
- Symptoms recorded were abdominal pain, bloating and changes in stool consistency, e.g. diarrhea or constipation.
This study shows (1) that many people who don't have Celiac disease based on blood work, but have IBS symptoms, may still have wheat sensitivities; (2) that a significant portion of persons with IBS have an underlying food sensitivity similar to what you might see with an allergy; it seems that majority of symptomatic people have multiple food sensitivities (usually wheat and/or dairy); (3) that the elimination-challenge diet is a valid way to uncover underlying food sensitivities.
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Stress doesn’t cause IBS, but it can make your symptoms worse.
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